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Life Extending Power of Resveretrol |
Research has proved that resveratrol majorly extends the lifespan of the
yeast Saccharomyces cerevisiae. Resveratrol also prolongs the lifespan
of the worm Caenorhabditis elegans and fruit fly Drosophila melanogaster.
Italian scientists carried out interesting research. Using a short-lived
fish, Nothobranchius furzeri, with a life span of about nine weeks, they
proved that a maximal dose of resveratrol increased the median lifespan
by as much as 56%. Compared with the control fish at nine weeks, that is
by the end of the latter's life, the fish supplemented with resveratrol
showed a lot higher general swimming activity and better learning to
avoid an unpleasant stimulus. There was a little increase of mortality
in young fish caused by resveratrol. This was because of its weak toxic
action that stimulated the defense mechanisms and resulted in the life
span prolongation.
Resveratrol has also been seen to have counteracted the detrimental
effects of a high-fat diet in mice. The high fat diet was made by adding
hydrogenated coconut oil to the standard diet, it provided 60% of energy
from fat, and the mice on it consumed about 30% more calories than the
mice on the usual diet. Both the mice fed the usual diet and the
high-fat diet plus 22 mg/kg resveratrol had a 30% lower risk of death
compared to the mice on the high-fat diet. |
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Resveratrol Benefits and Red Wine |
Drinking red wine is known to be a way to increase healthy antioxidants
in our bodies, but we all know the harmful effects of alcohol.
Resveratrol is a compound found in red wine that creates these
antioxidants and is known to have anti-aging properties. Several studies
have proven that resveratrol helps with the aging process by activating
certain longevity
enzymes that influence the genes that regulate the aging process,
resveratrol and weight loss is also been documented. Other research has
shown resveratrol to: be a phytoestrogen, which helps protect breast and
prostate tissue; reduce LDL (bad cholesterol) and to maintain and
promote healthy HDL (good cholesterol) levels; support skin tissues by
lessening free radicals; and also support healthy circulation.
Resveratrol has shown to aid in cancer patients (including breast
cancer) and diabetes patients. |
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Resveratrol - The Great Anti-aging Solution |
Resveratrol is the ingredient that may actually activate a dormant
anti-aging gene called Sirt1 (the first gene of the Sirtuin genes) in
the human body, resveratrol also has anti-inflammatory properties.
In an experiment, mice that were administered resveratrol along with an
unhealthy diet lived thirty percent longer than mice given a standard
diet but with no resveratrol. The first mice were more active and had
more energy. Studies have also shown the benefits of resveratrol and
blood pressure.
Resveratrol is present in red wine. This nutrient is derived from the
skins of grapes. The “French Paradox” describes how the French have a
lower rate of heart disease despite the fact that they eat more fatty
foods. The answer may be in the wine they habitually drink.
The only problem is, high concentrations of resveretrol needed to see
the real benefits. If you could drink that much wine, the alcohol
content couldn’t be good for the brain cells.
So, scientists are making a synthetic pill that would have the effects
of resveretrol.
There are plenty of resveratrol supplements in the stores These won’t
have any of the detrimental side effects that a synthetic chemical drug
might have if it gets released to the public in the next five years. The
supplements are available in tablet and powder form and can “clump up”
in the digestive track, and so not get absorbed. On top of that, most of
these products have a small amount of resveratrol, so you have to shop
wisely.
Liquid resveratrol is up to 200 times more absorbable. A supplement must
be nano size, to be more bio-available in the digestive process. Then it
will go into the cells more easily. Resveratrol can help hugely with
energy and weight loss. It may also keep at bay diseases like diabetes
and Alzheimer’s. There are also benefits of resveratrol for diabetes, as
a dietary supplement, even resveratrol cream for wrinkles and lowering
cholestrol. A lot of people look for cheap resveratrol, but what is the
best resveratrol brand? |
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Resveratrol - Anti-Aging Fountain of Youth |
Featured on 60 Minutes, Fox News Channel, CNN, Oprah, and the Rachel Ray
Show, Resveretrol is earning its reputation as the anti-aging supplement
that does work along with its bioavailability its a fighter against
blood sugar, breast cancer. Resveratrol can be found in cream and
capsules, in fact Resveratrol caps tend to be very popular. Resveratrol
is a substance found in red wine that has been shown to lengthen and
strengthen the lives of subjects in clinical testing. Even Barbara
Walters Resveratrol special was aired not so long ago.
According to lab tests, we could live 30 percent longer than the average
life expectancy. That indeed is a huge difference! There are more than
80,000 people in the United States alone, who are over the age of one
hundred. The experiments suggest that number to grow rapidly in the
years to come. It hence offers encouragement to the baby boomer
generation, or anyone who wants to look younger and feel fresher.
Resveratrol is also designed to make you feel better on the inside.
Featuring omega 3 fatty acids that are so difficult to pick up in your
everyday diet - substances with anti-oxidant effects present in fish,
nuts, and certain oils - you can have control over your metabolism, have
more energy, and build more muscle.
Resveratrol will help you to fight nutritional and genetic diseases,
such as diabetes and Alzheimer's, respectively. You do not always have
to be a slave to your genetic health history.
Most importantly, these ingredients have no known side effects that
would discourage you from giving them a try and reaching your maximum
potential. This is indeed encouraging, because our bodies are not the
same, and thus do not always obtain the same results. It is important
that even if you do not get as much out of Resveretrol as someone else,
there are no health risks involved.
What does resveratrol grapes mean? Well its actually resveratrol grape
juice or resveratrol grape seed extract that is providing the benefits. |
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What Is Resveratrol? |
Resveratrol (trans-resveratrol) is a phytoalexin produced by many plants
when attacked by pathogens such as bacteria or fungi. Resveratrol can
also be produced by chemical synthesis and is available in stores as a
nutritional supplement derived mainly from Japanese knotweed. In animal
experiments, anti-cancer, anti-inflammatory, blood-sugar-lowering and
other beneficial cardiovascular effects of resveratrol have been seen.
However, these results have not been replicated in humans. Resveratrol
is present in the skin of red grapes and also in red wine, but
apparently not in good enough amounts to explain the French paradox.
Experiments have shown that resveratrol treatment prolonged the life of
fruit flies, nematode worms and short-lived fish but did not increase
the life span of mice. In 1997, Jang found out that topical resveratrol
applications prevented skin cancer development in mice treated with a
carcinogen. However, no results of human clinical trials for cancer have
been reported. Johan Auwerx (at the Institute of Genetics and Molecular
and Cell Biology in Illkirch, France) and coauthors in their online
journal Cell, noted that mice fed resveratrol for fifteen weeks had
better treadmill endurance than controls.
In a study involving 123 Finnish adults, those born with certain
increased variations of the SIRT1 gene had more rapid rates of
metabolisms, helping them to burn energy faster—hinting that the same
pathway shown in the lab mice works in humans.
Researchers at the Weill Medical College of Cornell University found out
that dietary supplementation with resveratrol greatly reduced building
up of plaque in animal brains, a component of Alzheimer and other
Neurodegenerative diseases. In mice, resveratrol supplements taken
orally produced large reductions in brain plaque in the hypothalamus
(-90%), striatum (-89%), and medial cortex (-48%) regions of the brain.
In humans there is a widely accepted theory that oral doses of
resveratrol may reduce beta amyloid plaque linked with aging changes in
the brain. Researchers hold a theory that one mechanism for eradication
of plaque is the ability of resveratrol to chelate ie bind copper. |
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Proven health benefits of Resveratrol |
Resveratrol is a plant extract, obtained from only a certain number of
plants – particularly when they are under attack from pathogens. Plants
are attacked by many of the same bacteria and fungi that invade humans,
so resveratrol has been seen to have the same anti bacterial and anti
fungal properties in our bodies, as they already do in plants.
Resveratrol is not naturally produced in the human body and so the
ingestion of such a substance can be greatly beneficial on several
levels.
As is usual these days, when the mainstream media catches on to the
latest scientific breakthrough – there is a lot of public hype
surrounding the product. Resveratrol however, has received little
attention from the media – and has thus been used as a “secret” solution
to many problems. Because of its broad range of benefits, people are
using resveratrol for a variety of reasons. Here are a few of its proven
health benefits:
- Anti-inflammatory action
- Anti-carcinogenic properties
- Regulation of blood sugar
- Increase of athletic endurance
- Lower incidence of Alzheimers disease
- Lower incidence of stroke
- Lower incidence of heart disease
- Protection from radiation exposure on cellular level
For humans, a larger consumption of resveratrol compared to plants is
required to induce the same positive effects. This is possible by
consuming a manufactured supplement with resveratrol as the main
ingredient. |
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Resveratrol Supplements |
Resveratrol was first isolated in the year 1940 from the roots of
hellebore. In 1963, it was then isolated from the roots of Polygonum
Cuspidatum - a traditional Chinese and Japanese plant known to have
medicinal value. In 1992 Resveratrol was considered to explain some of
the life long consumption benefits of red wine. Since then, there have
been many research reports that have proven Resveratrol can prevent or
slow down a whole variety of illnesses.
In 1997, Jang reported that resveratrol inhibits carcinogenesis at
different stages. They saw that topical application of resveratrol
lessened the number of skin tumors in mice by as much as 98%. This
triggered resveratrol research around the globe. Since then, systemic
administration of resveratrol has been seen to inhibit, and restrict the
growth of tumors in a wide variety of rodent cancerous models. The
research models indicate that resveratrol could inhibit cancerous tumor
development using multiple mechanisms.
Resveratrol (3,4’,5-trihydroxystilbene) belongs to a group of
polyphenolic compounds called stilbenes. Some kinds of plants produce
Resveratrol and other stilbenes as a reaction to stress, injury, fungal
infection, and ultraviolet (UV) radiation. It is found in the skins of
certain kinds of red grapes, in peanuts, blueberries, some pines (Scots
pine, eastern white pine) and also in the roots and stalks of Japanese
knotweed (hu zhang in China) and giant knotweed.
Resveratrol got its deserved attention from the public after a study
released by Harvard Medical School in November 2006. In this study,
researchers David Sinclair and Rafael de Cabo, Ph.D., determined that
resveratrol prolonged longevity of obese mice and reversed nearly all of
the changes in gene expression patterns occuring in mice on high calorie
diets—some of which are associated with diabetes, heart disease, and
other significant diseases linked to obesity. |
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The many benefits of Resveratrol Supplements |
Resveratrol has been shown to prevent and shrink cancer and to have
strong antiviral anti-fungal properties. It has also been shown to have
neuro-protective, anti-aging, anti-inflammatory and life-prolonging
effects.
Resveratrol and Angiogenesis.
Angiogenesis is necessary for most cancer tumors to grow beyond a 2-3 mm
diameter. At a dose of 2.5-100mg per kg of body weight, Resveratrol has
been seen to prevent the tumor activated neovascularization. The
suppression by resveratrol could be responsible in its effect on
preventing tumor growth.
In resveratrol derived from dietary foods, like red wine, there was some
proof of therapeutic effects. At higher doses, the protective effects
and results were more dramatic.
Resveratrol and drug metabolism.
In studies using livers of rats treated with resveratrol, it has been
seen that it may prevent carcinogens, simultaneaously increasing the
body's capacity to get rid of harmful molecules.
Resveratrol as Antioxidant.
Reactive oxygen species are seen to have a damaging role to DNA and
other macromolecules. Resveratrol has a antioxidant capacity that can
also be related to its chemo preventative effects. Resveratrol has also
been shown to prevent LDL oxidation. In stroke prone rats, resveratrol
greatly reduced oxidative stress markers.
Resveratrol and cholesterol
In 1982 resveratrol was proven to inhibit the deposit of triglycerides
and cholesterol in rat livers.
Resveratrol and postmenopausal women
In some systems, Resveratrol has been seen to act as a phytooestrogen.
Research is continuing to see if there is a firm connection for
cardioprotective effects.
Resveratrol and immunity
Resveratrol has been seen to lessen and prevent many types of
inflammation, as in arthritis, psoriasis, and crohn's disease,
cardiovascular disease and cancer. Resveratrol could represent a very
good alternative to current treatments for chronic inflammation as
aspirin can have a detrimental effect on the lining of the stomach,
which resveratrol does not. Resveratrol also enhances immune response in
mice.
Other Resveratrol studies.
Resveratrol has been seen to protect against hearing loss, act as an
analgesic, lessen injury to spinal cord, liver, kidneys, lungs,
intestine, and colon. The results determine that Resveratrol is not
limited to help against brain and heart injuries and has an even wider
scope.
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Understanding Resveratrol
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You hear about Resveratrol in the news, your friends mention the anti-aging effects of Resveratrol and its connection to red wine - but what on earth is Reserveratrol and how does it affect you? Well to begin with Resveratrol was first isolated in 1940 from the plant hellebore. It wasn't until 1992 when a connection was made with the life prolong benefits of red wine and Resveratrol. Then further studies on animals have shown that resveratrol may assist in cancer treatment, prolong life and cardiovascular health.
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Where can I buy Resveratrol?
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Several prominent nutritional companies have formulated their brand of resveratrol. For example Jarrow Formulas carries Resveratrol Synergy, while Olympian Labs carries Clinical Resveratrol. Several other nutrition companies like Source Naturals, Nature's Way, Country Life and Life Extension, have their own formulations of resveratrol. VNF Nutrition, the online nutrition company also carries a wide range of resveratrol brands for their customer base.
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