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Progesterone works with estrogen to maintain reproductive organs, prepare for conception and pregnancy, and regulate menstrual cycles. One of the many things estrogen does is to thicken and build the endometrium (the lining of a woman's uterus) each month. This is the body's natural way of getting ready for pregnancy. Progesterone is one of the main components that cause this lining to shed each month when pregnancy doesn't happen. This shedding is your menstrual period.
Before menopause, a few women may experience the absence of regular periods for 6 months or more. This condition, known as secondary amenorrhea, is sometimes caused by not having enough progesterone.
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