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Buy Ubiquinol, Buy Coq-10 - Latest Research |
Research associates maintaining healthy CoQ10 levels with optimal heart,
neurological as well as immune health. It is also linked with high
levels of energy. With age, maintaining the heart and nerves becomes
even more challenging and important. The cholesterol-lowering drugs
taken like statins can reduce CoQ10 levels, which can be dangerous.
Ubiquinone supplements can restore CoQ10 plasma levels, but its
effectiveness usually starts to decrease in those over 40. Such
diminished CoQ10 levels may have some minor effects that can get more
pronounced with time.
The ubiquinone form of CoQ-10, especially the more bioavailable forms
contain volumes of proven data backing its efficacy. Most of clinical
and experimental investigations have been done using ubiquinone, showing
its positive nutritional support in the fight against aging including
angina pectoris, congestive heart failure, hypertension, etc. Also,
ubiquinone is an important cofactor for the synthesis of ATP energy
production and both the forms must be present for efficient ATP
production. Hence, Co-Q10 (ubiquinone) remains a crucial supplement for
maintaining a healthy lifestyle with optimal health.
Healthy people under age 40 can meet their needs with the CoQ10
supplements that have been used for 30 years. However, those over 40 or
who are suffering from oxidative stress may use the pre-converted,
active antioxidant form. Huge doses of Co-Q10 are not recommended for
healthy individuals. Nevertheless, many clinical studies have shown the
safety and tolerability of high doses of CoQ10. Ubiquinol is also
available as it is the reduced form of COQ10 |
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Breakdown of Ubiquinol and Understanding CO-Q10 and Ubiquone |
Ubiquinol is the reduced form of coenzyme Q10 or CoQ10. The safety and
bioavailability of ubiquinol, this naturally occurring lipid-soluble
nutrient, were evaluated recently for the first time in single-blind,
placebo-controlled studies with healthy individuals. No clinically
relevant changes were spotted in results of standard laboratory tests,
physical examination and vital signs. Following single or multiple-doses
of ubiquinol in healthy volunteers, considerable absorption of ubiquinol
supplements from the gastrointestinal tract was seen, and no safety
concerns were noted on standard laboratory tests for safety or on
assessment of adverse events.
Ubiquinol has been seen to prevent the expression of tumour- promoting
factors in adenoma and carcinoma colon cancer cells brought on by
dietary fat. High intake of dietary fat promotes colon carcinogenesis.
Ubiquinone has shown unprecedented anti-aging effects compared to
placebo and so this new version of CoQ10 could revolutionize the way
several age-related disorders are both prevented and treated. For this
ubiquinone form of CoQ10 to be utilized correctly, it first must be
reduced in the body to its active metabolite known as ubiquinol. While
most ubiquinone is reduced to ubiquinol on its own, the best way to
supplement with CoQ10 would be to take it in as supplements, in its
ready-to-use ubiquinol form. However, there is a possibility that too
high a dose of ubiquinol supplements in the body may actually cause more
harm than good so care should be taken regarding the dosage. |
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Utility of CoQ10 |
Persuasive evidence has been provided to show that CoQ10 could help
protect against a host of age-related disorders.
Based on a vast volume of research, CoQ10 has emerged as one of today’s
most popular dietary supplements. New delivery systems have been
developed that transport more CoQ10 into the bloodstream than the
previous versions.
Providing greater quantities of Co-Q10 to the body is of great
importance, as scientific studies show that higher CoQ10 blood levels
produce greater benefits. In probably the most significant breakthrough
in the history of the dietary supplement industry, a way has been
discovered to deliver the highest concentrations of the most
biologically active form of coenzyme Q10 to the bloodstream.
This improved version of CoQ10 not only absorbs up to eight times
better, but also has demonstrated anti-aging effects never known before.
The ubiquinone form of CoQ-10 to be properly utilized, it first must be
reduced in the body to its active metabolite which is called ubiquinol.
While most ubiquinone is naturally reduced to ubiquinol, the optimal way
to supplement with CoQ10 would be to orally take it in its ready-to-use
ubiquinol form.
Ubiquinol is very unstable, and it has been difficult to make it
available as a dietary supplement. After many years of research, Japan’s
largest producer of coenzyme Q10 has developed a patented method which
is able to stabilize ubiquinol so that it can be ingested in capsule
form. |
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Declining Ubiquinol Levels with Age |
The reduced, active antioxidant form of Coenzyme Q10 (CoQ10) is known as
Ubiquinol. It is generally produced within healthy bodies. Ubiquinol is
CoQ10 that has been converted in order to be used in the cellular energy
production process. It is indispensable for energy production, and is
the strongest lipid-soluble
antioxidant.
Ubiquinol protects the body’s cells from oxidative stress which can
damage proteins, lipids and DNA.
The body has to convert ubiquinone into ubiquinol in order to generate
cellular energy. Otherwise, the body’s energy production process cannot
be completed and energy levels cannot be maintained. Hence, both are
crucial to sustaining your body’s energy. That is why declines in
ubiquinol means less cellular energy and less protection against
oxidative stress. When this happens, free radicals are produced which
damages the body’s cells, including proteins, lipids and DNA. Ubiquinol
is necessary for a strong defense against this cellular oxidative damage
and must be replenished to maintain good health.
Several scientific reports indicate that sudden decreases in ubiquinone
levels and increased oxidative stress are related to the aging process
and with many age-related conditions. When young, you readily produce
all of the CoQ10 you can use and easily convert it into ubiquinol. The
main form of CoQ10 in the plasma and tissues of a healthy individual is,
in fact, the reduced ubiquinol form.
Factors like age can affect the body’s ability to produce and metabolize
CoQ10. Some reasons may be increased metabolic demand, insufficient
dietary intake, oxidative stress, etc. Some reports claim this decline
becomes clear around 40 years of age, although it can begin as early as
20 for some. With age, supplementation with CoQ10 and/or ubiquinol
becomes very important to maintaining optimum health. |
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Importance of Ubiquinol |
Ubiquinol - New Improved Form of CoQ10
The amount of Coenzyme Q10 (CoQ10) absorbed is of great importance as
higher CoQ10 blood levels provide many more benefits.
Researchers found that Ubiquinol, the new form of CoQ10, was 40% more
effective than conventional CoQ10 in slowing the aging process in mice.
The actual video footage of the mice shows that the aging group of mice
receiving no supplementation is unable to move or respond, developing
lesions in and around the eye with spinal and limb deformities and a
discolored coat. These pathological events are typical signs of
degenerative aging suffered by humans. Aging mice supplemented with
Ubiquinol, on the other hand, are alert, responsive and energetic with
perfect health and youthful appearance.
Coenzyme Q10 exists in both ubiquinol and ubiquinone forms, but they
have majorly different roles to play in the body. For the first time in
the market, a stabilized ubiquinol form of CoQ10 is available in capsule
form. When compared to conventional (ubiquinone) CoQ10 supplements, the
benefits of ubiquinol are far more great.
A recent peer-reviewed study measured the absorption in humans
supplementing with 150 mg and 300 mg of ubiquinol. Far less doses of
ubiquinol produce about the same blood (plasma) levels compared with
much higher doses of ubiquinone. In fact, it takes 8-times more
ubiquinone to increase CoQ10 blood levels to what can be attained with
much lesser doses of ubiquinol.
Ubiquinol has an ability to stay biologically active in the body much
longer.
The greater absorption and ability to remain bioavailable over a greater
sustained time period may mean unprecedented anti-senescent effects
observed with new ubiquinol compared to ubiquinone.
Benefits of Coenzyme Q10
Coenzyme Q10 is a critical component in the cellular energy production
cycle. CoQ10 is produced in all cells of the human body. It helps
produce cellular ATP (adenosine triphosphate), which supplies energy to
all cell functions.
Coenzyme Q10 is an antioxidant having great importance as a free radical
scavenger. CoQ10 maintains the stability of the cell membrane, protects
DNA from free radical induced oxidative damage, and promotes the recycle
of Vitamin E in the body. The human body gradually loses its ability to
synthesize CoQ10 with age. Research has proven that supplementation with
CoQ10 may support normal heart function, protect DNA from free radical
induced oxidative damage, promote and maintain healthy energy levels. |
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Benefits of Ubiquinol |
Ubiquinol contributes to cardiovascular and cognitive health, increased energy and
stamina, and overall health and wellbeing. It
offers crucial antioxidant benefits and even regenerates other
antioxidants, like Vitamin C and Vitamin E. Ubiquinol plays an important role in
supplying energy to the organs such as the
heart, kidneys, liver and lungs and
may also help compensate for the age-related reduction in the body’s ability
to convert CoQ10 into ubiquinol. It
may help protect cells from free radical
damage. It maintains your natural energy, health and youthful vigor at any age. Ubiquinol ignites the energy production
in cells that gives energy to your
vital organs.
It protects your cells from the constant attack by free radicals.
Your body produces this powerful antioxidant everyday when
young. But its not possible to sustain your natural production forever,
and so supplementation is important for healthy aging.
In a study,
aged rats were chosen to measure how long they could run on a
treadmill. The control group using no CoQ10 showed a little decline in
running times. The group receiving the ubiquinone form of CoQ10 had a
60% increase in running time whereas the group receiving ubiquinol had a
150% increase in running time.
Type 2 diabetics suffer from elevated oxidative stress
bringing about autonomic nervous system dysfunction. Japanese researchers
proved that as the day proceeded, so did levels of oxidative stress. This
oxidative stress depleted ubiquinol levels more rapidly than ubiquinone. In
fact, diabetics had approximately 75% less ubiquinol than the
non-diabetic control group.
Researchers at the University of Tokyo found that people with certain types of liver disease including
cirrhosis, hepatitis, and hepatoma, suffered from elevated oxidative
stress which lead to a decrease in ubiquinol levels. This happened without
any reduction in the levels of ubiquinone.
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Answers to frequently asked questions
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Q. What is ubiquinone or CoQ10?
A. CoQ10 or ubiquinone is a vitamin-like substance present
in every cell in the body. It is converted into a vital antioxidant and
is crucial to energy production. Ubiquinone has been taken in supplement
form by millions worldwide to increase
energy, and improve cardiac and cognitive health. Ubiquinone protects
cells from free radicals, regenerates other antioxidants and helps
cells to generate the energy to fuel the vital organs in the body.
Q. Isn’t ubiquinol another name for CoQ10?
A. Ubiquinol is the active antioxidant form of ubiquinone, and is
responsible for the powerful benefits associated with
CoQ10. It is easily assimilated and utilized by
the body. Preliminary research shows that ubiquinol is a lot more
effective than ubiquinone at raising CoQ10 plasma level.
Q. How do the two forms work in the body?
A. Ubiquinone - whether
produced naturally within the body or ingested -
has to be converted into ubiquinol to generate cellular energy.
Without proper conversion and optimal levels of both forms, the body
cannot meet the constant and demanding energy needs of
vital organs, or protect cells from harmful free radicals.
Q. Can I produce and convert CoQ10 naturally?
A. The body’s natural production of CoQ10 declines with age, as does
the ability to convert the nutrient into ubiquinol. CoQ10 production may
start to decline as
early as age 20. In fact for some, CoQ10 levels within the heart and kidneys
have dropped more than 25 percent by age 40.
Q. Why are CoQ10 levels so important?
A. A growing body of research associates maintaining healthy CoQ10
levels with optimal health of heart, neurological and immune systems. It is also
linked with high levels of energy. As we age, maintaining the heart
and nerves becomes more and more important. Additionally,
cholesterol-lowering drugs such as statins can reduce CoQ10 levels,
which can impact the quality of life for many of us.
Q. If I feel fine healthwise, will a CoQ10 supplement be sufficient?
A. In most of us, Ubiquinone supplements restore CoQ10 plasma levels to some degree, but its effectiveness generally begins to
get less in those over 40
as a result of the diminished ability to convert the nutrient into ubiquinol.
These diminished CoQ10 levels may have subtle effects initially that can
become more pronounced with time.
Q. Is it true that the new ubiquinol product is making the standard CoQ10 ubiquinone
product obsolete?
A. That is not true. The ubiquinone form of CoQ10, especially highly bioavailable
forms like CoQsol-CF™, CoQ10 with Omega-3, and CoQ10 with Bioperine™
have so much solid data backing its efficacy. Most of
clinical and experimental investigations have been done using ubiquinone,
demonstrating its positive nutritional support in the fight against
aging including angina pectoris, congestive heart failure, hypertension,
and several other conditions. Also we can't forget that ubiquinone is an
essential cofactor for the synthesis of ATP energy production. Thus both
forms are necessary for efficient ATP production. So, CoQ10 (ubiquinone)
will always be a vital supplement for maintaining a healthy lifestyle.
Q. Which from of CoQ10 do I require?
A. Healthy people under age 40 can meet their needs with the same CoQ10
supplements that have been used effectively for 30 years.
Those over 40 should think of
using the pre-converted, active antioxidant form.
Q. What is the average recommended dosage?
A. An initial dose is typically 200-300 mg
per day for around three weeks, followed by a maintenance dose of 100 mg
per day after that.
Q. Can I use both ubiquinone and ubiquinol?
A. Yes. Although great doses of CoQ10 are not suggested for healthy
individuals, there have been many clinical studies to assess the
safety and tolerability of high doses of CoQ10. In an ALS study, CoQ10
was safe and well tolerated in 31 subjects treated with doses as high as
3,000 mg/day for 8 months. NEUROLOGY 2005; 65: 1834-1836.
Q. Why wasn’t ubiquinol previously available?
A. Scientists identified ubiquinol’s crucial role in the body over 30
years ago. However, it took more than a decade of research, and advanced
technology developed and patented by Kaneka Corporation, to isolate the
compound outside the body.
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More about Ubiquinol and Coq10 |
Ubiquinol and Coq10 help you reduce the signs of normal aging.
They help you to feel more alert and responsive.
They help maintain your vitality, by keeping blood levels high in Co
Q10.
They assist you to maintain blood pressure levels within the normal
range.
They promote healthy blood circulation in your body and thereby have a
more efficient heart.
Ubiquinol and Coq10 provide a boost to your immune system while promoting
your healthy immune system.They help support your immune system by
providing a defense against free radicals.
They help support your nervous system and promotes an active mind.
Your brain is one of the most active organs in your body and requires
constant energy which they provide.
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What you need to know about COQ-10?
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Other names for COQ10 are Coenzyme Q10, Co Q10, Ubiquinone, Vitamin Q. CoQ10 is a naturally-occuring compound found in every cell in the body.
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Apparent benefits of COQ10
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- Heart failure
- Cardiomyopathy
- Heart Attack Prevention
- High Blood Pressure
- Diabetes
- Gum Disease
- Kidney Failure
- Migraine
- Counteract Prescription Drug Effects
- Parkinson's disease
- Weight loss
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What is the recommended dosage?
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A typical CoQ10 dosage may be 30 to 90 mg per day, but spread over several doses, but depending on the circumstance the recommended amount can be as high as 200 mg per day. Since
CoQ10 is fat-soluble it is better absorbed when taken with a meal that contains oil or fat. One thing to keep in mind is that the clinical effect is not immediate and may take up to 8 weeks.
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Where can I purchase COQ10?
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There are many popular nutritional companies that have their own formulations of COQ10, such as Jarrow Formulas, Bluebonnet and Life Extension. VNF Nutrition, online nutrional superstore, has a wide range of popular Ubiquinol brands and CO-Q10 for your requirements.
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